Publications

Are mitochondria the key to reduce the age-dependent decline in axon growth after spinal cord injury? Sutherland TC, Geoffroy CG, Neural Regen Res 2021;16:1444-5

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A novel Oct4/Pou5f1-like non-coding RNA controls neural maturation and mediates developmental effects of ethanol. Salem NA, Mahnke AH,  Tseng AM,  Garcia CR, Jahromi HK, Geoffroy CG, Miranda RC Neurotoxicol Teratol​,. Jan-Feb 2021;83:106943. doi:10.1016/j.ntt.2020.106943. Epub 2020 Nov 20.

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The influence of neuron-extrinsic factors and aging on injury progression and axonal repair in the central nervous system

Sutherland TC, Geoffroy CG. Front Cell Dev Biol. 2020;8:190. Published 2020 Mar 25. doi:10.3389/fcell.2020.00190

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Blockade of IL-17 signaling reverses alcohol-induced liver injury and excessive alcohol drinking in mice

Xu J et al. Blockade of IL-17 signaling reverses alcohol-induced liver injury and excessive alcohol drinking in mice. JCI Insight. 2020;5(3):e131277. Published 2020 Feb 13. doi:10.1172/jci.insight.131277

 

Oligodendrocytic but not neuronal Nogo restricts corticospinal axon sprouting after CNS injury.

Meves JM, Geoffroy CG, Kim ND, Kim JJ, Zheng B. Experimental neurology. 2018; 309:32-43. NIHMSID: NIHMS1502842 PubMed [journal] PMID:30055160, PMCID: PMC6139267 https://doi.org/10.1016/j.expneurol.2018.07.013

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Adult rat myelin enhances axonal outgrowth from neural stem cells.

Poplawski GHD, Lie R, Hunt M, Kumamaru H, Kawaguchi R, Lu P, Schäfer MKE, Woodruff G, Robinson J, Canete P, Dulin JN, Geoffroy CG, Menzel L, Zheng B, Coppola G, Tuszynski MH. Science translational medicine. 2018; 10(442). PubMed [journal] PMID: 29794059. DOI: 10.1126/scitranslmed.aal2563

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Leucine Zipper-Bearing Kinase Is a Critical Regulator of Astrocyte Reactivity in the Adult Mammalian CNS.

Chen M, Geoffroy CG, Meves JM, Narang A, Li Y, Nguyen MT, Khai VS, Kong X, Steinke CL, Carolino KI, Elzière L, Goldberg MP, Jin Y, Zheng B. Cell reports. 2018; 22(13):3587-3597. NIHMSID: NIHMS957794 PubMed [journal] PMID: 29590625, PMCID: PMC5905706. doi.org/10.1038/srep31482

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The age factor in axonal repair after spinal cord injury: A focus on neuron-intrinsic mechanisms.

Geoffroy CG, Meves JM, Zheng B. Neuroscience letters. 2017; 652:41-49. NIHMSID: NIHMS828683 PubMed [journal] PMID: 27818358, PMCID: PMC5415436

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Leucine Zipper-bearing Kinase promotes axon growth in mammalian central nervous system neurons.

Chen M, Geoffroy CG, Wong HN, Tress O, Nguyen MT, Holzman LB, Jin Y, Zheng B. Scientific reports. 2016; 6:31482. PubMed [journal] PMID: 27511108, PMCID: PMC4980599

 

Evidence for an Age-Dependent Decline in Axon Regeneration in the Adult Mammalian Central Nervous System.

Geoffroy CG, Hilton BJ, Tetzlaff W, Zheng B. Cell reports. 2016; 15(2):238-46. NIHMSID: NIHMS769142 PubMed [journal] PMID: 27050519, PMCID: PMC5050004

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The role of IL-17 signaling in regulation of the liver-brain axis and intestinal permeability in Alcoholic Liver Disease.

Ma HY, Xu J, Liu X, Zhu Y, Gao B, Karin M, Tsukamoto H, Jeste DV, Grant I, Roberts AJ, Contet C, Geoffroy C, Zheng B, Brenner D, Kisseleva T. Current pathobiology reports. 2016; 4(1):27-35. NIHMSID: NIHMS761714 PubMed [journal] PMID: 27239399, PMCID: PMC4878828

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Effects of PTEN and Nogo Codeletion on Corticospinal Axon Sprouting and Regeneration in Mice.

Geoffroy CG, Lorenzana AO, Kwan JP, Lin K, Ghassemi O, Ma A, Xu N, Creger D, Liu K, He Z, Zheng B. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2015; 35(16):6413-28. PubMed [journal] PMID: 25904793, PMCID: PMC4405557

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Myelin-associated inhibitors in axonal growth after CNS injury.

Geoffroy CG, Zheng B. Current opinion in neurobiology. 2014; 27:31-8. NIHMSID: NIHMS567337 PubMed [journal] PMID: 24608164, PMCID: PMC4122599

 

NgR1 and NgR3 are receptors for chondroitin sulfate proteoglycans.

Dickendesher TL, Baldwin KT, Mironova YA, Koriyama Y, Raiker SJ, Askew KL, Wood A, Geoffroy CG, Zheng B, Liepmann CD, Katagiri Y, Benowitz LI, Geller HM, Giger RJ. Nature neuroscience. 2012; 15(5):703-12. NIHMSID: NIHMS357951 PubMed [journal] PMID: 22406547, PMCID: PMC3337880

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Role of myelin proteins on axon regeneration and sprouting

Geoffroy CG. Medecine sciences : M/S. 2011; 27(2):132-5. PubMed [journal] PMID: 21382319

 

Assessing spinal axon regeneration and sprouting in Nogo-, MAG-, and OMgp-deficient mice.

Lee JK, Geoffroy CG, Chan AF, Tolentino KE, Crawford MJ, Leal MA, Kang B, Zheng B. Neuron. 2010; 66(5):663-70. NIHMSID: NIHMS206496 PubMed [journal] PMID: 20547125, PMCID: PMC2896331

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Generation of an EphA4 conditional allele in mice.

Herrmann JE, Pence MA, Shapera EA, Shah RR, Geoffroy CG, Zheng B. Genesis (New York, N.Y. : 2000). 2010; 48(2):101-5. NIHMSID: NIHMS167068 PubMed [journal] PMID: 20014422, PMCID: PMC2819605

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Engineering of dominant active basic helix-loop-helix proteins that are resistant to negative regulation by postnatal central nervous system antineurogenic cues.

Geoffroy CG, Critchley JA, Castro DS, Ramelli S, Barraclough C, Descombes P, Guillemot F, Raineteau O. Stem cells (Dayton, Ohio). 2009; 27(4):847-56. PubMed [journal] PMID: 19350686

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A Cre-lox approach for transient transgene expression in neural precursor cells and long-term tracking of their progeny in vitro and in vivo.

Geoffroy CG, Raineteau O. BMC developmental biology. 2007; 7:45. PubMed [journal] PMID: 17504531, PMCID: PMC1885435