Publications
Targeting PTEN but not SOCS3 resists an age-dependent decline in promoting axon sprouting.
Geoffroy CG*, Meves JM, Mun Kim HJ, Romaus-Sanjurjo D, Sutherland TC, Li JJ, Suen J, Sanchez JJ, Zheng B*. * co-corresponding authors. iScience, 2022 Nov 18;25(11):105383.
In vivo peptide-based delivery of a gene-modifying enzyme into cells of the central nervous system.
Allen JK, Sutherland TC, Prater AR, Geoffroy CG*, Pellois JP*. * co-corresponding authors. Science Advances. 2022 Sep 28;8(39):eabo2954.
Dietz VA, Roberts N, Knox K, Moore S, Pitonak M, Barr C, Centeno J, Leininger S, New KC, Nowell P, Rodreick M, Geoffroy CG, Stampas A, Dulin JN. Frontiers in Cellular Neuroscience. 2022 Sep 7;16:462.
Sefiani A, Rusyn I, Geoffroy CG*. Sci. Rep. 12 (1), 13125. 2022.
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Evaluation of the Cardiometabolic Disorders after Spinal Cord Injury in Mice.
Ghnenis, A.B.; Jones, C.; Sefiani, A.; Douthitt, A.J.; Reyna, A.J.; Rutkowski, J.M.; Geoffroy, C.G. Biology 2022, 11, 495. https://doi.org/10.3390/biology11040495
Osteopenia in a Mouse Model of Spinal Cord Injury: Effects of Age, Sex and Motor Function.
Hook, M.A.; Falck, A.; Dundumulla, R.; Terminel, M.; Cunningham, R.; Sefiani, A.; Callaway, K.; Gaddy, D.; Geoffroy, C.G. . Biology 2022, 11, 189. https://doi.org/10.3390/biology11020189
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Age-Dependent Decline in Neuron Growth Potential and Mitochondria Functions in Cortical Neurons.
Sutherland TC, Sefiani A, Horvat D, Huntington TE, Lei Y, West AP, Geoffroy CG*. Cells. 2021 Jun 29;10(7). doi: 10.3390/cells10071625.
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Sefiani A, Geoffroy CG- Front Neurosci. 2021;15:682259. Published 2021 Jun 18. doi:10.3389/fnins.2021.682259
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Are mitochondria the key to reduce the age-dependent decline in axon growth after spinal cord injury?
Sutherland TC, Geoffroy CG, Neural Regen Res 2021;16:1444-5
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Salem NA, Mahnke AH, Tseng AM, Garcia CR, Jahromi HK, Geoffroy CG, Miranda RC Neurotoxicol Teratol​,. Jan-Feb 2021;83:106943. doi:10.1016/j.ntt.2020.106943. Epub 2020 Nov 20.
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Sutherland TC, Geoffroy CG. Front Cell Dev Biol. 2020;8:190. Published 2020 Mar 25. doi:10.3389/fcell.2020.00190
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Xu J et al. Blockade of IL-17 signaling reverses alcohol-induced liver injury and excessive alcohol drinking in mice. JCI Insight. 2020;5(3):e131277. Published 2020 Feb 13. doi:10.1172/jci.insight.131277
Oligodendrocytic but not neuronal Nogo restricts corticospinal axon sprouting after CNS injury.
Meves JM, Geoffroy CG, Kim ND, Kim JJ, Zheng B. Experimental neurology. 2018; 309:32-43. NIHMSID: NIHMS1502842 PubMed [journal] PMID:30055160, PMCID: PMC6139267 https://doi.org/10.1016/j.expneurol.2018.07.013
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Adult rat myelin enhances axonal outgrowth from neural stem cells.
Poplawski GHD, Lie R, Hunt M, Kumamaru H, Kawaguchi R, Lu P, Schäfer MKE, Woodruff G, Robinson J, Canete P, Dulin JN, Geoffroy CG, Menzel L, Zheng B, Coppola G, Tuszynski MH. Science translational medicine. 2018; 10(442). PubMed [journal] PMID: 29794059. DOI: 10.1126/scitranslmed.aal2563
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Chen M, Geoffroy CG, Meves JM, Narang A, Li Y, Nguyen MT, Khai VS, Kong X, Steinke CL, Carolino KI, Elzière L, Goldberg MP, Jin Y, Zheng B. Cell reports. 2018; 22(13):3587-3597. NIHMSID: NIHMS957794 PubMed [journal] PMID: 29590625, PMCID: PMC5905706. doi.org/10.1038/srep31482
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The age factor in axonal repair after spinal cord injury: A focus on neuron-intrinsic mechanisms.
Geoffroy CG, Meves JM, Zheng B. Neuroscience letters. 2017; 652:41-49. NIHMSID: NIHMS828683 PubMed [journal] PMID: 27818358, PMCID: PMC5415436
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Leucine Zipper-bearing Kinase promotes axon growth in mammalian central nervous system neurons.
Chen M, Geoffroy CG, Wong HN, Tress O, Nguyen MT, Holzman LB, Jin Y, Zheng B. Scientific reports. 2016; 6:31482. PubMed [journal] PMID: 27511108, PMCID: PMC4980599
Geoffroy CG, Hilton BJ, Tetzlaff W, Zheng B. Cell reports. 2016; 15(2):238-46. NIHMSID: NIHMS769142 PubMed [journal] PMID: 27050519, PMCID: PMC5050004
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Ma HY, Xu J, Liu X, Zhu Y, Gao B, Karin M, Tsukamoto H, Jeste DV, Grant I, Roberts AJ, Contet C, Geoffroy C, Zheng B, Brenner D, Kisseleva T. Current pathobiology reports. 2016; 4(1):27-35. NIHMSID: NIHMS761714 PubMed [journal] PMID: 27239399, PMCID: PMC4878828
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Effects of PTEN and Nogo Codeletion on Corticospinal Axon Sprouting and Regeneration in Mice.
Geoffroy CG, Lorenzana AO, Kwan JP, Lin K, Ghassemi O, Ma A, Xu N, Creger D, Liu K, He Z, Zheng B. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2015; 35(16):6413-28. PubMed [journal] PMID: 25904793, PMCID: PMC4405557
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Myelin-associated inhibitors in axonal growth after CNS injury.
Geoffroy CG, Zheng B. Current opinion in neurobiology. 2014; 27:31-8. NIHMSID: NIHMS567337 PubMed [journal] PMID: 24608164, PMCID: PMC4122599
NgR1 and NgR3 are receptors for chondroitin sulfate proteoglycans.
Dickendesher TL, Baldwin KT, Mironova YA, Koriyama Y, Raiker SJ, Askew KL, Wood A, Geoffroy CG, Zheng B, Liepmann CD, Katagiri Y, Benowitz LI, Geller HM, Giger RJ. Nature neuroscience. 2012; 15(5):703-12. NIHMSID: NIHMS357951 PubMed [journal] PMID: 22406547, PMCID: PMC3337880
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Role of myelin proteins on axon regeneration and sprouting
Geoffroy CG. Medecine sciences : M/S. 2011; 27(2):132-5. PubMed [journal] PMID: 21382319
Assessing spinal axon regeneration and sprouting in Nogo-, MAG-, and OMgp-deficient mice.
Lee JK, Geoffroy CG, Chan AF, Tolentino KE, Crawford MJ, Leal MA, Kang B, Zheng B. Neuron. 2010; 66(5):663-70. NIHMSID: NIHMS206496 PubMed [journal] PMID: 20547125, PMCID: PMC2896331
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Generation of an EphA4 conditional allele in mice.
Herrmann JE, Pence MA, Shapera EA, Shah RR, Geoffroy CG, Zheng B. Genesis (New York, N.Y. : 2000). 2010; 48(2):101-5. NIHMSID: NIHMS167068 PubMed [journal] PMID: 20014422, PMCID: PMC2819605
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Geoffroy CG, Critchley JA, Castro DS, Ramelli S, Barraclough C, Descombes P, Guillemot F, Raineteau O. Stem cells (Dayton, Ohio). 2009; 27(4):847-56. PubMed [journal] PMID: 19350686
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Geoffroy CG, Raineteau O. BMC developmental biology. 2007; 7:45. PubMed [journal] PMID: 17504531, PMCID: PMC1885435